Oysters and Vibrios as a Model for Disease Dynamics in Wild Animals.

TitleOysters and Vibrios as a Model for Disease Dynamics in Wild Animals.
Publication TypeJournal Article
Year of Publication2016
AuthorsLe Roux F, K Wegner M, Polz MF
JournalTrends Microbiol
Date Published2016 Jul

Disease dynamics in the wild are influenced by a number of ecological and evolutionary factors not addressed by traditional laboratory-based characterization of pathogens. Here we propose the oyster, Crassostrea gigas, as a model for studying the interaction of the environment, bacterial pathogens, and the host in disease dynamics. We show that an important first step is to ask whether the functional unit of pathogenesis is a bacterial clone, a population, or a consortium in order to assess triggers of disease outbreaks and devise appropriate monitoring tools. Moreover, the development of specific-pathogen-free (SPF) oysters has enabled assessment of the infection process under natural conditions. Finally, recent results show the importance of microbial interactions and host genetics in determining oyster health and disease.

Alternate JournalTrends Microbiol.
PubMed ID27038736