Explaining microbial genomic diversity in light of evolutionary ecology.

TitleExplaining microbial genomic diversity in light of evolutionary ecology.
Publication TypeJournal Article
Year of Publication2014
AuthorsCordero OX, Polz MF
JournalNat Rev Microbiol
Volume12
Issue4
Pagination263-73
Date Published2014 Apr
ISSN1740-1534
KeywordsArchaea, Bacteria, Bacterial Physiological Phenomena, Biodiversity, Biological Evolution, Ecosystem, Genetic Variation, Microbial Interactions, Selection, Genetic
Abstract

Comparisons of closely related microorganisms have shown that individual genomes can be highly diverse in terms of gene content. In this Review, we discuss several studies showing that much of this variation is associated with social and ecological interactions, which have an important role in the population biology of wild populations of bacteria and archaea. These interactions create frequency-dependent selective pressures that can either stabilize gene frequencies at intermediate levels in populations or promote fast gene turnover, which presents as low gene frequencies in genome surveys. Thus, interpretation of gene-content diversity requires the delineation of populations according to cohesive gene flow and ecology, as micro-evolutionary changes arise in response to local selection pressures and population dynamics.

DOI10.1038/nrmicro3218
Alternate JournalNat. Rev. Microbiol.
PubMed ID24590245
Grant ListP30‑ES002109 / ES / NIEHS NIH HHS / United States