Hong Xue

Hong Xue
Graduate Student
Contact Information: 

 

Department of Civil and Environmental Engineering
MIT 48-418
77 Massachusetts Avenue
Cambridge, MA 02139

Phone: (617) 253-8650
Fax: (617) 253-7475
Email: hongxue(at)mit.edu

Research - Education - Publications: 

Research Interests

  • Horizontal gene transfer and the origin of the new genes.
  • Genetic relationship among bacteria in microbial communities.
  • Environmental genomics with emphasis on composition of the mobile DNA pool.
  • Adaptive evolution of bacteria to their changing environment.

Publications

  1. Xue H, Guo R, Wen Y, Liu D, Huang L: An abundant DNA binding protein from the hyperthermophilic archaeon Sulfolobus shibatae affects DNA supercoiling in a temperature-dependent fashion. J Bacteriol 2000 Jul;182(14):3929-33
  2. Wang G, Guo R, Bartlam M, Xue H, Yang H, Liu Y, Huang L, Rao Z: Expression, purification, crystallization and preliminary X-ray analysis of a DNA-binding protein from Methanococcus jannaschii. Acta Crystallogr D Biol Crystallogr 2002 Jul; 58(Pt 7): 1240-2
  3. Bu D, Zhao Y, Cai L, Xue H, Zhu X, Lu H, Zhang J, Sun S, Ling L, Zhang N, Li G, Chen R. Topological structure analysis of the protein-protein interaction network in budding yeast. Nucleic Acids Res. 2003 May 1; 31(9): 2443-50
  4. Cui Q, Tong Y, Xue H, Huang L, Feng Y, Wang J. Two conformations of archaeal Ssh10b: The origin of its temperature dependent interaction with DNA. J Biol Chem. 2003 Dec 19; 278(51): 51015-22. Epub 2003 Sep 30.
  5. Wang G, Guo R, Bartlam M, Yang H, Xue H, Liu Y, Huang L, Rao Z. Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeon Methanococcus jannaschii. Protein Sci. 2003 Dec; 12(12): 2815-2822.
  6. Guo R, Xue H, and Huang L. Ssh10b, a conserved thermophilic archaeal protein, binds RNA in vivo. Mol Microbiol. 2003 Dec; 50(5): 1605-15